Combined Vaccines

The Combined Use of rHVT-H5 and rHVT-F Vector Vaccines in the Hatchery Enhances Immunity against Highly Pathogenic Avian Influenza H5N1 and Velogenic Newcastle Disease Viral Infections in Commercial Chickens

Highly pathogenic avian influenza H5N1 and Newcastle disease viral infections cause severe illness in chickens and vaccination is a strategic tool of controlling these diseases. Hence, this study was conducted to evaluate the efficacy of using both recombinant herpesvirus of turkey (rHVT-H5 and rHVT-F) vector vaccines at day-old, in the hatchery, under field conditions. Vaccinated chickens were...

Safety of immunization during pregnancy: a review of the evidence of selected inactivated and live attenuated vaccines.

Vaccine-preventable infectious diseases are responsible for significant maternal, neonatal, and young infant morbidity and mortality. While there is emerging scientific evidence, as well as theoretical considerations, indicating that certain vaccines are safe for pregnant women and fetuses, policy formulation is challenging because of perceived potential risks to the fetus. This report presents...

Combined Hepatitis Vaccines Equal in Safety and Immunogenicity to Monovalent Vaccines

[Frontiers in Bioscience 7, d43-52, January 1, 2002] 43 IMMUNOTHERAPY OF CANCER USING HEAT SHOCK PROTEINS

1. Abstract 2. Introduction 3. Stress protein families and their immunological properties 3.1. Chaperoning properties 3.2. Peptide binding properties 3.3. Hsps interact with APCs 4. Immunogenicity of hsps 4.1. Tumor-derived hsp vaccines 4.2. Hsp-peptide based vaccines 4.3. Hsp-protein based vaccines 4.4. Hsp-based DNA vaccines 4.5. Hsp fusion protein vaccines 4.6. Cell-based vaccines 5. Improve...

Development of Inactivated Newcastle Disease Vaccine using Palm Oil as an Adjuvant

The experiments aimed to develop the inactivated Newcastle disease (ND) vaccine in the form of water in oil (WO) and water in oil in water (WOW) using palm oil, which is easily found in tropical countries, and to study the effect of vitamin E in the form of dl-α-tocopheryl acetate for improving the efficacy of inactivated ND vaccine prepared from palm oil. Two hundred and twenty, thirty five da...

Cell-based Hyper-interleukin 6 or Hyper-interleukin 11 secreting vaccines combined with low dose cyclophosphamide in an orthotopic murine prostate cancer model

BACKGROUND Cell based vaccines encoding Hyper-IL-6 (H6) and Hyper-IL-11 (H11) present high activity in murine melanoma and renal cancer model. We evaluated the efficacy of cellular vaccines modified with H6 or H11 combined with cyclophosphamide in orthotopic murine prostate cancer model. MATERIAL AND METHODS TRAMP cells were transduced with H6 and H11 cDNA (TRAMP-H6 and TRAMP-H11). An orthoto...